The intriguing role of polymorphonuclear neutrophils in antitumor reactions

作者：Emma Di Carlo, Guido Forni, Pier‐Luigi Lollini, Mario P. Colombo, Andrea Modesti, Piero Musiani · 发表于：Blood · 年份：2001 · DOI：10.1182/blood.v97.2.339 · 被引用次数：417 · 研究领域：Chemokine receptors and signaling、Cell Adhesion Molecules Research、Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Polymorphonuclear neutrophils (PMNs) are the most abundant circulating blood leukocytes. They provide the first-line defense against infection and are potent effectors of inflammation. In addition, their release of soluble chemotactic factors guides the recruitment of both nonspecific and specific