Structure-radical scavenging activity relationships of flavonoids

作者：Dragan Amić, Dušanka Davidović-Amić, Drago Bešlo, Nenad Trinajstić · 发表于：Institutional Repository of the Ruđer Bošković Institute (Ruđer Bošković Institute) · 年份：2003 · 被引用次数：582 · 研究领域：Phytochemicals and Antioxidant Activities、Free Radicals and Antioxidants、Agriculture and Biological Studies

The relationship between the structural characteristics of 29 flavonoids and their antiradical activity was studied. The obtained results suggest that the free radical scavenger potential of these polyphenolic compounds closely depends on the particular substitution pattern of free hydroxyl groups on the flavonoid skeleton. The possible mechanism of action of flavonoids lacking B ring OHs as free radical scavengers has been proposed.