Hormonal regulation of glycogen synthase phosphorylation in rabbit skeletal muscle.

作者：Virender S. Sheorain, Balwant S. Khatra, Thomas R. Soderling · 发表于：Journal of Biological Chemistry · 年份：1982 · DOI：10.1016/s0021-9258(18)34801-4 · 被引用次数：45 · 研究领域：Adipose Tissue and Metabolism、Muscle metabolism and nutrition、Muscle Physiology and Disorders

Phosphorylation of rabbit skeletal muscle glycogen synthase in vivo in response to hormones was investigated.Methods were developed to purify the synthase without altering its kinetic parameters, thereby indicating constancy of the synthase phosphorylation state.The enzyme from control rabbits had an activity ratio (-glucose-6-P/+glucose-6-P) of 0.24, K, for glucose-6-