Ethnic Variations in Myopia and Ocular Biometry Among Adults in a Rural Community in China: The Yunnan Minority Eye Studies

作者：Chen‐Wei Pan, Qin Chen, Xun Sheng, Jun Li, Zhiqiang Niu, Hua Zhou, Tao Wei, Yuansheng Yuan, Hua Zhong · 发表于：Investigative Ophthalmology & Visual Science · 年份：2015 · DOI：10.1167/iovs.14-16357 · 被引用次数：32 · 研究领域：Ophthalmology and Visual Impairment Studies、Corneal surgery and disorders、Visual perception and processing mechanisms

PURPOSE: To determine the prevalence of myopia and ocular biometry in population-based samples of ethnic Yi and Han people living in an inland rural community in China. METHODS: A random cluster sampling strategy was used to select ethnic Han and Yi adults aged 50 years or older living in Yunnan. Refractive error was determined by subjective refraction and ocular biometric parameters, including axial length (AL), anterior chamber depth (ACD), vitreous chamber depth (VCD), and lens thickness (LT), which were measured using an Echoscan. RESULTS: Adults of Yi ethnicity had lower prevalence of myopia (10.3% vs. 8.1%; P = 0.02) and high myopia (2.3% vs. 1.6%; P = 0.10) than their counterparts of Han ethnicity. The prevalence of myopia increased with age (P for trend < 0.05), whereas the mean AL did not differ significantly among age groups in both ethnic groups (both P for trend > 0.05). In multivariate analysis, time spent outdoors was associated with myopia (P = 0.003) and AL (P < 0.001) but not high myopia (P = 0.33). No interaction effect was detected between ethnicity and other risk factors on myopia (all P > 0.05). Adjustment for lens nuclear opacity score reduced the excess prevalence of myopia in Han ethnicity by 37.5%. CONCLUSIONS: There was little evidence showing that ethnic disparities existed in the prevalence and risk factors between the major and minor ethnic groups living in the same communities in rural China. The "cohort effect" on myopia observed in many other p...