SMN2 splice modulators enhance U1–pre-mRNA association and rescue SMA mice

作者：James J. Palacino, Susanne E. Swalley, Cheng Song, Atwood K. Cheung, Lei Shu, Xiaolu Zhang, Mailin Van Hoosear, Youngah Shin, Donovan N. Chin, Caroline Gubser Keller, Martin Beibel, Nicole Renaud, Thomas M. Smith, Michael Salcius, Xiaoying Shi, Marc Hild, Rebecca Servais, Monish Jain, Lin Deng, Caroline P. Bullock, Michael D. McLellan, Sven Schuierer, Leo Murphy, Marcel J. J. Blommers, Cecile Blaustein, Frada Berenshteyn, Arnaud Lacoste, Jason R. Thomas, Guglielmo Roma, Gregory A. Michaud, Brian S. Tseng, Jeffery A. Porter, Vic E. Myer, John A. Tallarico, Lawrence G. Hamann, Daniel Curtis, Mark C. Fishman, William F. Dietrich, Natalie A. Dales, Rajeev Sivasankaran · 发表于：Nature Chemical Biology · 年份：2015 · DOI：10.1038/nchembio.1837 · 被引用次数：437 · 研究领域：Neurogenetic and Muscular Disorders Research、RNA Research and Splicing、RNA and protein synthesis mechanisms