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Detection of Antigenic Differences in Isologous Host-Tumor Systems by Pretreatment with Heavily Irradiated Tumor Cells

作者:Láśzló Révész · 发表于:The Mouseion at the JAXlibrary (Jackson Laboratory) · 年份:1960 · 被引用次数:128 · 研究领域:Polyamine Metabolism and Applications、Immune Cell Function and Interaction、RNA Interference and Gene Delivery

Summary It was confirmed that antigenic differences exist between methylcholanthrene-induced sarcomas of recent origin and their isologous hosts. No similar differences were demonstrable with spontaneous carcinomas and lymphomas of recent origin, while long-transplanted lines could provoke incompatibility reactions, probably due to genetic deviations between host and tumor in the course of time.