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Presence of a virulence-associated plasmid in Yersinia pseudotuberculosis

作者:P. Gemski, Janet R. Lazere, Thomas A. Casey, John A. Wohlhieter · 发表于:Infection and Immunity · 年份:1980 · DOI:10.1128/iai.28.3.1044-1047.1980 · 被引用次数:241 · 研究领域:Yersinia bacterium, plague, ectoparasites research、Pharmacological Effects of Natural Compounds、Plant-based Medicinal Research

We have shown that Yersinia pseudotuberculosis can possess plasmids which are similar in size and function to the previously described Vwa plasmids of Y. enterocolitica. These plasmids are associated with the production of V and W antigens (calcium dependency) and pathogenicity of the organism. Further investigation of these plasmids from Y. pseudotuberculosis and Y. enterocolitica with restriction endonucleases revealed significant differences in their fragmentation pattern.