Colorado Tick Fever and Related Coltivirus Infections

作者：Anthony A. Marfin, Grant L. Campbell · 发表于：ASM Press eBooks · 年份：2014 · DOI：10.1128/9781555816490.ch8 · 被引用次数：13 · 研究领域：Viral Infections and Vectors、Vector-Borne Animal Diseases、Animal Disease Management and Epidemiology

Accounts of “mountain fever” first appeared in the mid-19th century among Rocky Mountain settlers. Although this term likely included several infectious diseases, a relatively mild form of fever was endemic in the area, associated with headache, arthralgia, and myalgia that occurred in the spring and early summer and very likely represented Colorado tick fever (CTF). CTF virus (CTFV) is the prototypic member of the Coltivirus genus, a member of the family Reoviridae. A few other tick-borne coltiviruses have been associated with rare cases of human illness, including Salmon River virus isolated from a patient with CTF-like illness in Idaho and Eyach virus isolated in Europe. This chapter first discusses the etiologic agent, biology, life cycle and zoonotic hosts of CTFV. Then, it describes epidemiology, geography, clinical features, diagnosis, treatment, and prevention of CTF.