M. Espelosin

发表论文 20 篇 · 总被引 402 次 · h-index 10

代表论文

Targeting RNA-Mediated Toxicity in C9orf72 ALS and/or FTD by RNAi-Based Gene Therapy (2019 · Molecular Therapy: Nucleic Acids · 被引 89)
Design, Synthesis, and Biological Evaluation of First-in-Class Dual Acting Histone Deacetylases (HDACs) and Phosphodiesterase 5 (PDE5) Inhibitors for the Treatment of Alzheimer's Disease. (2016 · Journal of Medicinal Chemistry · 被引 71)
Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease. (2018 · European journal of medicinal chemistry · 被引 55)
PLA2 G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. (2020 · Progress in neurobiology · 被引 38)
Multitarget Approach for the Treatment of Alzheimer`s Disease: Inhibition of Phosphodiesterase 9 (PDE9) and Histone Deacetylases (HDACs) covering diverse selectivity profiles. (2019 · ACS Chemical Neuroscience · 被引 33)
Discovery of in Vivo Chemical Probes for Treating Alzheimer's Disease: Dual Phosphodiesterase 5 (PDE5) and Class I Histone Deacetylase Selective Inhibitors. (2018 · ACS Chemical Neuroscience · 被引 29)