Mark J. Osborn

发表论文 107 篇 · 总被引 5841 次 · h-index 36

代表论文

• Enhanced prime editing systems by manipulating cellular determinants of editing outcomes (2021 · Cell · 被引 704)
• Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins (2022 · Cell · 被引 558)
• Phage-assisted evolution and protein engineering yield compact, efficient prime editors (2023 · Cell · 被引 264)
• Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity (2022 · Nature Biotechnology · 被引 216)
• Efficient site-specific integration of large genes in mammalian cells via continuously evolved recombinases and prime editing (2024 · Nature Biomedical Engineering · 被引 161)
• Base editor correction of COL7A1 in recessive dystrophic epidermolysis bullosa patient-derived fibroblasts and iPSCs (2019 · Journal of Investigative Dermatology · 被引 88)