Yingyi Chen

发表论文 33 篇 · 总被引 1491 次 · h-index 21

代表论文

• Identification of a cellularly active SIRT6 allosteric activator (2018 · Nature Chemical Biology · 被引 245)
• A novel SIRT6 activator ameliorates neuroinflammation and ischemic brain injury via EZH2/FOXC1 axis (2020 · Acta Pharmaceutica Sinica B · 被引 112)
• Crystal Structures of PI3Kα Complexed with PI103 and Its Derivatives: New Directions for Inhibitors Design. (2014 · ACS Medicinal Chemistry Letters · 被引 101)
• BitterX: a tool for understanding bitter taste in humans (2016 · Scientific Reports · 被引 81)
• Mechanism of allosteric activation of SIRT6 revealed by the action of rationally designed activators (2020 · Acta Pharmaceutica Sinica B · 被引 76)
• Targeting a cryptic allosteric site of SIRT6 with small-molecule inhibitors that inhibit the migration of pancreatic cancer cells (2021 · Acta Pharmaceutica Sinica B · 被引 70)