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Alex Aliper

机构:Hong Kong Science and Technology Parks Corporation, Technology Innovation Institute, Insilicos (United States), INSEAD, Insilicogen (South Korea), Insilico Medicine (United States)

发表论文 94 篇 · 总被引 5510 次 · h-index 27

代表论文

  • Discovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation (2025 · Nature Communications · 被引 18)
  • Conformational restriction of hinge carboxamide leading to potent lactam-based PKMYT1 inhibitors (2026 · Bioorganic & Medicinal Chemistry · 被引 3)
  • Advancing target discovery through disease-specific integration of multi-modal target identification models and comprehensive benchmarking system (2026 · Scientific Reports · 被引 1)
  • An Internal Sulfur–Lone Pair Interaction Enabled the Discovery of Potent and Sub‐Family Selective PKMYT1 Inhibitors (2026 · ChemMedChem · 被引 1)
  • AlphaFold Kinase Optimizer: Enhancing Virtual Screening Performance Through Automated Refinement of AlphaFold ‐Based Kinase Structures (2025 · Proteins Structure Function and Bioinformatics · 被引 1)
  • Discovery ofHighly Potent and Selective, Orally BioavailableBTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads (2026 · Journal of Medicinal Chemistry)