Trixie Wagner

机构：Novartis (Switzerland), Novartis Institutes for BioMedical Research

发表论文 246 篇 · 总被引 6426 次 · h-index 37

代表论文

• Quantitative and functional characterisation of extracellular vesicles after passive loading with hydrophobic or cholesterol-tagged small molecules (2023 · Journal of Controlled Release · 被引 51)
• Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease (2021 · Journal of Medicinal Chemistry · 被引 36)
• Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria (2021 · Journal of Medicinal Chemistry · 被引 32)
• Discovery and Optimization of Novel SUCNR1 Inhibitors: Design of Zwitterionic Derivatives with a Salt Bridge for the Improvement of Oral Exposure (2020 · Journal of Medicinal Chemistry · 被引 32)
• Integrated and automated high-throughput purification of libraries on microscale (2022 · SLAS TECHNOLOGY · 被引 27)
• Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood (2020 · Journal of Medicinal Chemistry · 被引 27)