Yoshiaki Isobe

机构：Sumitomo Dainippon Pharma (Japan)

发表论文 164 篇 · 总被引 2581 次 · h-index 29

代表论文

• Crystal Structures and Structure–Activity Relationships of Imidazothiazole Derivatives as IDO1 Inhibitors (2014 · ACS Medicinal Chemistry Letters · 被引 144)
• Synthesis and evaluation of 2-substituted 8-hydroxyadenines as potent interferon inducers with improved oral bioavailabilities (2004 · Bioorganic & Medicinal Chemistry · 被引 80)
• Increase in neurogenesis and neuroblast migration after a small intracerebral hemorrhage in rats (2007 · Neuroscience Letters · 被引 78)
• Structural analysis reveals TLR7 dynamics underlying antagonism (2020 · Nature Communications · 被引 71)
• Synthesis and Biological Evaluation of 8-Oxoadenine Derivatives as Toll-like Receptor 7 Agonists Introducing the Antedrug Concept (2010 · Journal of Medicinal Chemistry · 被引 49)
• Synthesis and structure–activity relationships of phenothiazine carboxylic acids having pyrimidine-dione as novel histamine H1 antagonists (2009 · Bioorganic & Medicinal Chemistry Letters · 被引 46)