Sabrina Köcher

机构：Universität Hamburg, University Medical Center Hamburg-Eppendorf, Institute of Radiotherapy and Nuclear Medicine

发表论文 22 篇 · 总被引 358 次 · h-index 12

代表论文

• Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma (2012 · Radiotherapy and Oncology · 被引 70)
• Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase (2012 · Nucleic Acids Research · 被引 47)
• Dual PI3K/mTOR Inhibitor NVP-BEZ235 Enhances Radiosensitivity of Head and Neck Squamous Cell Carcinoma (HNSCC) Cell Lines Due to Suppressed Double-Strand Break (DSB) Repair by Non-Homologous End Joining (2020 · Cancers · 被引 41)
• Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1 (2016 · Oncotarget · 被引 31)
• Functional crosstalk between DNA damage response proteins 53BP1 and BRCA1 regulates double strand break repair choice (2015 · Radiotherapy and Oncology · 被引 29)
• Second-Generation Antiandrogen Therapy Radiosensitizes Prostate Cancer Regardless of Castration State through Inhibition of DNA Double Strand Break Repair (2020 · Cancers · 被引 21)