Ling-Heng Kong

机构：Sun Yat-sen University, Sun Yat-sen University Cancer Center

发表论文 49 篇 · 总被引 1627 次 · h-index 21

代表论文

• Tumor-derived lactate promotes resistance to bevacizumab treatment by facilitating autophagy enhancer protein RUBCNL expression through histone H3 lysine 18 lactylation (H3K18la) in colorectal cancer (2023 · Autophagy · 被引 433)
• Inflammation promotes resistance to immune checkpoint inhibitors in high microsatellite instability colorectal cancer (2022 · Nature Communications · 被引 159)
• Dickkopf 1 impairs the tumor response to PD-1 blockade by inactivating CD8+ T cells in deficient mismatch repair colorectal cancer (2021 · Journal for ImmunoTherapy of Cancer · 被引 64)
• Neoadjuvant camrelizumab plus apatinib for locally advanced microsatellite instability-high or mismatch repair-deficient colorectal cancer (NEOCAP): a single-arm, open-label, phase 2 study (2024 · The Lancet Oncology · 被引 50)
• PD-1 blockade in neoadjuvant setting of DNA mismatch repair-deficient/microsatellite instability-high colorectal cancer (2020 · OncoImmunology · 被引 48)
• Neoadjuvant Immunotherapy Leads to Major Response and Low Recurrence in Localized Mismatch Repair–Deficient Colorectal Cancer (2023 · Journal of the National Comprehensive Cancer Network · 被引 43)