Karen L. Leach

机构：Pfizer (United States), Centers for New Horizons

发表论文 72 篇 · 总被引 4872 次 · h-index 36

代表论文

• The Site of Action of Oxazolidinone Antibiotics in Living Bacteria and in Human Mitochondria (2007 · Molecular Cell · 被引 284)
• Type 3 protein kinase C localization to the nuclear envelope of phorbol ester-treated NIH 3T3 cells. (1989 · The Journal of Cell Biology · 被引 219)
• Linezolid, the first oxazolidinone antibacterial agent (2011 · Annals of the New York Academy of Sciences · 被引 196)
• Discovery of PF-06928215 as a high affinity inhibitor of cGAS enabled by a novel fluorescence polarization assay (2017 · PLoS ONE · 被引 168)
• 3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding (2004 · Journal of Medicinal Chemistry · 被引 161)
• Direct Demonstration of NFATp Dephosphorylation and Nuclear Localization in Activated HT-2 Cells Using a Specific NFATp Polyclonal Antibody (1995 · Journal of Biological Chemistry · 被引 135)