Lenora B. Cieslinski

机构：GlaxoSmithKline (United States)

发表论文 30 篇 · 总被引 2226 次 · h-index 23

代表论文

• Discovery of BRL 50481 [3-(N,N-dimethylsulfonamido)-4-methyl-nitrobenzene], a Selective Inhibitor of Phosphodiesterase 7: In Vitro Studies in Human Monocytes, Lung Macrophages, and CD8+ T-Lymphocytes (2004 · Molecular Pharmacology · 被引 167)
• Identification, characterization and functional role of phosphodiesterase isozymes in human airway smooth muscle. (1993 · Journal of Pharmacology and Experimental Therapeutics · 被引 166)
• 1,4-Cyclohexanecarboxylates: Potent and Selective Inhibitors of Phosophodiesterase 4 for the Treatment of Asthma (1998 · Journal of Medicinal Chemistry · 被引 150)
• Suppression of human inflammatory cell function by subtype‐selective PDE4 inhibitors correlates with inhibition of PDE4A and PDE4B (1999 · British Journal of Pharmacology · 被引 145)
• Coexpression of human cAMP-specific phosphodiesterase activity and high affinity rolipram binding in yeast. (1992 · Journal of Biological Chemistry · 被引 139)
• Cloning and expression of cDNA for a human low-Km, rolipram-sensitive cyclic AMP phosphodiesterase. (1990 · Molecular and Cellular Biology · 被引 133)