Bruno Marchand

机构：Gilead Sciences (United States)

发表论文 260 篇 · 总被引 2573 次 · h-index 26

代表论文

• Acetyl-CoA carboxylase inhibition disrupts metabolic reprogramming during hepatic stellate cell activation (2020 · Journal of Hepatology · 被引 229)
• Structural basis of HIV inhibition by translocation-defective RT inhibitor 4′-ethynyl-2-fluoro-2′-deoxyadenosine (EFdA) (2016 · Proceedings of the National Academy of Sciences · 被引 112)
• Hepatitis B Virus X Protein Function Requires Zinc Binding (2019 · Journal of Virology · 被引 48)
• Discovery of GS-7682, a Novel 4′-Cyano-Modified C -Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys (2024 · Journal of Medicinal Chemistry · 被引 17)
• Combinations of an acetyl CoA carboxylase inhibitor with hepatic lipid modulating agents do not augment antifibrotic efficacy in preclinical models of NASH and fibrosis (2022 · Hepatology Communications · 被引 15)
• Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII) (2017 · Bioorganic & Medicinal Chemistry Letters · 被引 11)