Dustin S. Siegel

机构：Gilead Sciences (United States)

发表论文 42 篇 · 总被引 6787 次 · h-index 16

代表论文

• Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses (2017 · Science Translational Medicine · 被引 1639)
• Therapeutic efficacy of the small molecule GS-5734 against Ebola virus in rhesus monkeys (2016 · Nature · 被引 1611)
• Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease (2018 · mBio · 被引 1519)
• Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1- f ][triazin-4-amino] Adenine C -Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses (2017 · Journal of Medicinal Chemistry · 被引 670)
• GS-5734 and its parent nucleoside analog inhibit Filo-, Pneumo-, and Paramyxoviruses (2017 · Scientific Reports · 被引 524)
• Discovery of an Oral Respiratory Syncytial Virus (RSV) Fusion Inhibitor (GS-5806) and Clinical Proof of Concept in a Human RSV Challenge Study (2015 · Journal of Medicinal Chemistry · 被引 128)