Eisuke Murakami

机构：Flower Hospital · ORCID：0000-0003-2315-2819

发表论文 64 篇 · 总被引 2395 次 · h-index 24

代表论文

• Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice (2020 · Cell Reports · 被引 541)
• Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C -Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV (2021 · Journal of Medicinal Chemistry · 被引 90)
• Therapeutic treatment with an oral prodrug of the remdesivir parental nucleoside is protective against SARS-CoV-2 pathogenesis in mice (2022 · Science Translational Medicine · 被引 83)
• Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells (2021 · Antimicrobial Agents and Chemotherapy · 被引 63)
• Off-Target In Vitro Profiling Demonstrates that Remdesivir Is a Highly Selective Antiviral Agent (2020 · Antimicrobial Agents and Chemotherapy · 被引 57)
• Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection (2021 · Science Translational Medicine · 被引 42)