Lijie Zhao

机构：Zhejiang Sci-Tech University · ORCID：0000-0001-7944-5739

发表论文 39 篇 · 总被引 1586 次 · h-index 17

代表论文

Discovery of Highly Potent and Efficient PROTAC Degraders of Androgen Receptor (AR) by Employing Weak Binding Affinity VHL E3 Ligase Ligands (2019 · Journal of Medicinal Chemistry · 被引 215)
Discovery of ARD-2585 as an Exceptionally Potent and Orally Active PROTAC Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer (2021 · Journal of Medicinal Chemistry · 被引 145)
Strategies toward Discovery of Potent and Orally Bioavailable Proteolysis Targeting Chimera Degraders of Androgen Receptor for the Treatment of Prostate Cancer (2021 · Journal of Medicinal Chemistry · 被引 141)
RNA m5C oxidation by TET2 regulates chromatin state and leukaemogenesis (2024 · Nature · 被引 85)
A highly potent PROTAC androgen receptor (AR) degrader ARD-61 effectively inhibits AR-positive breast cancer cell growth in vitro and tumor growth in vivo (2020 · Neoplasia · 被引 74)
Discovery of ARD-1676 as a Highly Potent and Orally Efficacious AR PROTAC Degrader with a Broad Activity against AR Mutants for the Treatment of AR + Human Prostate Cancer (2023 · Journal of Medicinal Chemistry · 被引 62)