Xiaotian Zhu

机构：China University of Mining and Technology · ORCID：0009-0000-9218-9864

发表论文 26 篇 · 总被引 980 次 · h-index 11

代表论文

• Crystal Structure of an Inactive Akt2 Kinase Domain (2003 · Structure · 被引 138)
• Structural studies of the binding of the anti-ulcer drug sucrose octasulfate to acidic fibroblast growth factor (1993 · Structure · 被引 89)
• Discovery of Aminoquinazolines as Potent, Orally Bioavailable Inhibitors of Lck:  Synthesis, SAR, and in Vivo Anti-Inflammatory Activity (2006 · Journal of Medicinal Chemistry · 被引 67)
• Structure-Based Design of Novel 2-Amino-6-phenyl-pyrimido[5′,4′:5,6]pyrimido[1,2- a ]benzimidazol-5(6 H )-ones as Potent and Orally Active Inhibitors of Lymphocyte Specific Kinase (Lck): Synthesis, SAR, and In Vivo Anti-Inflammatory Activity (2008 · Journal of Medicinal Chemistry · 被引 64)
• Novel 2-Aminopyrimidine Carbamates as Potent and Orally Active Inhibitors of Lck:  Synthesis, SAR, and in Vivo Antiinflammatory Activity (2006 · Journal of Medicinal Chemistry · 被引 61)
• Discovery of 4-amino-5,6-biaryl-furo[2,3-d]pyrimidines as inhibitors of Lck: Development of an expedient and divergent synthetic route and preliminary SAR (2007 · Bioorganic & Medicinal Chemistry Letters · 被引 50)