Lu Niu

机构：Sichuan University, West China Hospital of Sichuan University

发表论文 18 篇 · 总被引 330 次 · h-index 11

代表论文

• Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1's low clinical toxicity (2019 · Journal of Biological Chemistry · 被引 69)
• Cevipabulin-tubulin complex reveals a novel agent binding site on α-tubulin with tubulin degradation effect (2021 · Science Advances · 被引 66)
• Resveratrol Suppresses the Inducible Expression of CYP3A4 Through the Pregnane X Receptor (2014 · Journal of Pharmacological Sciences · 被引 35)
• The Natural Compound Withaferin A Covalently Binds to Cys239 of β-Tubulin to Promote Tubulin Degradation (2019 · Molecular Pharmacology · 被引 30)
• Discovery of Pyrrolo[3,2- d ]pyrimidin-4-one Derivatives as a New Class of Potent and Cell-Active Inhibitors of P300/CBP-Associated Factor Bromodomain (2019 · Journal of Medicinal Chemistry · 被引 19)
• Structure of 4′-demethylepipodophyllotoxin in complex with tubulin provides a rationale for drug design (2017 · Biochemical and Biophysical Research Communications · 被引 19)