Aman P. Singh

机构：University of Rochester Medicine, Takeda (United States), Neurological Surgery, Takeda (Japan), University of Rochester · ORCID：0000-0002-1886-2624

发表论文 42 篇 · 总被引 1109 次 · h-index 18

代表论文

• Model‐Based Cellular Kinetic Analysis of Chimeric Antigen Receptor‐T Cells in Humans (2020 · Clinical Pharmacology & Therapeutics · 被引 101)
• Bench‐to‐bedside translation of chimeric antigen receptor (CAR) T cells using a multiscale systems pharmacokinetic‐pharmacodynamic model: A case study with anti‐BCMA CAR‐T (2021 · CPT Pharmacometrics & Systems Pharmacology · 被引 51)
• Evolution of the Systems Pharmacokinetics-Pharmacodynamics Model for Antibody-Drug Conjugates to Characterize Tumor Heterogeneity and In Vivo Bystander Effect (2020 · Journal of Pharmacology and Experimental Therapeutics · 被引 30)
• From Cold to Hot: Changing Perceptions and Future Opportunities for Quantitative Systems Pharmacology Modeling in Cancer Immunotherapy (2022 · Clinical Pharmacology & Therapeutics · 被引 20)
• Development of a multiscale mechanistic modeling framework integrating differential cellular kinetics of CAR T‐ cell subsets and immunophenotypes in cancer patients (2023 · CPT Pharmacometrics & Systems Pharmacology · 被引 18)
• Updated results from first-in-human phase 1 dose-escalation trial of TAK-102, a GPC3-targeted armored CAR T cells, in patients with advanced solid tumors. (2024 · Journal of Clinical Oncology · 被引 16)