Huadong Sun

机构：First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University

发表论文 30 篇 · 总被引 975 次 · h-index 12

代表论文

• Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165 (2019 · Journal of Medicinal Chemistry · 被引 381)
• Identification of N -Methyl Nicotinamide and N -Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2) (2019 · Journal of Medicinal Chemistry · 被引 95)
• A novel function of CXCL10 in mediating monocyte production of proinflammatory cytokines (2017 · Journal of Leukocyte Biology · 被引 71)
• Identification of Imidazo[1,2- b ]pyridazine Derivatives as Potent, Selective, and Orally Active Tyk2 JH2 Inhibitors (2019 · ACS Medicinal Chemistry Letters · 被引 55)
• A Novel, Fully Human Anti–fucosyl-GM1 Antibody Demonstrates Potent In Vitro and In Vivo Antitumor Activity in Preclinical Models of Small Cell Lung Cancer (2018 · Clinical Cancer Research · 被引 50)
• Antibody–Drug Conjugate Bioanalysis Using Lb-LC–MS/MS Hybrid Assays: Strategies, Methodology and Correlation to Ligand-Binding Assays (2016 · Bioanalysis · 被引 49)