Minjie Zhang

机构：County Hospital, Xian Yang Central Hospital · ORCID：0000-0001-8561-0729

发表论文 194 篇 · 总被引 2785 次 · h-index 27

代表论文

• Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion (2025 · Journal of Medicinal Chemistry · 被引 31)
• Non-coding RNA mediates the defense-associated reverse transcriptase (DRT) anti-phage oligomerization transition (2025 · The EMBO Journal · 被引 5)
• Abstract 2996: TNG462, an MTA-cooperative PRMT5 inhibitor, demonstrates strong efficacy in combination with clinically relevant targeted therapies in MTAP-null preclinical models (2025 · Cancer Research · 被引 5)
• Pterostilbene mitigates the senescence of human dermal fibroblast cells by enhancing mitochondrial quality (2025 · Frontiers in Pharmacology · 被引 4)
• Abstract 462: TNG456 is a next-generation, brain-penetrant, MTA-cooperative PRMT5 inhibitor for the treatment of solid tumors with MTAP loss (2025 · Cancer Research · 被引 3)
• Paranodal instability driven by axonal mitochondrial accumulation in ischemic demyelination and cognitive decline (2025 · Molecular Psychiatry · 被引 3)