Jun Zhang

机构：Beijing Union University, China Pharmaceutical University, Shenzhen University, Peking University, Renji Hospital, Ruijin Hospital, Sir Run Run Shaw Hospital, Suzhou Municipal Hospital, Guangzhou Development Zone Hospital, Northern Jiangsu People's Hospital, State Key Laboratory of Oncogene and Related Genes, Shenzhen University Health Science Center, State Key Laboratory of Respiratory Disease, Shanghai Clinical Research Center, Huashan Hospital, Yangzhou University, Hainan Medical University, Guangzhou Medical University, Air Force Medical University · ORCID：0000-0002-6523-7573

发表论文 251 篇 · 总被引 8759 次 · h-index 49

代表论文

• Discovery of Novel PROTAC SIRT6 Degraders with Potent Efficacy against Hepatocellular Carcinoma (2024 · Journal of Medicinal Chemistry · 被引 56)
• Histone H1 deamidation facilitates chromatin relaxation for DNA repair (2025 · Nature · 被引 37)
• Dynamic ctDNA tracking stratifies relapse risk for triple negative breast cancer patients receiving neoadjuvant chemotherapy (2025 · Nature Communications · 被引 24)
• Targeting NAT10 attenuates homologous recombination via destabilizing DNA:RNA hybrids and overcomes PARP inhibitor resistance in cancers (2025 · Drug Resistance Updates · 被引 18)
• Tryptophan catabolites from microbiota ameliorate immune-mediated hepatitis through activating aryl hydrocarbon receptor of T cells (2025 · Gut Microbes · 被引 17)
• hnRNPA2B1 deacetylation by SIRT6 restrains local transcription and safeguards genome stability (2024 · Cell Death and Differentiation · 被引 8)