Xiaohua Chen

机构：Chinese Academy of Sciences, Shanghai Institute of Materia Medica, University of Chinese Academy of Sciences, State Key Laboratory of Drug Research, Tsinghua University · ORCID：0000-0003-3031-7095

发表论文 201 篇 · 总被引 8819 次 · h-index 50

代表论文

• A region-confined PROTAC nanoplatform for spatiotemporally tunable protein degradation and enhanced cancer therapy (2024 · Nature Communications · 被引 92)
• General Platform for Efficient and Modular Assembly of GalNAc–siRNA Conjugates via Primary Amines and o -Nitrobenzyl Alcohol Cyclization Photoclick Chemistry Enabling Rapid Access to Therapeutic Oligonucleotides (2025 · JACS Au · 被引 13)
• Cross‐Linking Profiling of Molecular Glue Degrader‐Induced E3 Ligase Interactome to Expand Target Space (2025 · Angewandte Chemie International Edition · 被引 12)
• Discovery Small-Molecule p300 Inhibitors Derived from a Newly Developed Indazolone-Focused DNA-Encoded Library (2024 · Bioconjugate Chemistry · 被引 12)
• Primary Amine-Based Photoclick Chemistry: From Concept to Diverse Applications in Chemical Biology and Medicinal Chemistry (2025 · Accounts of Chemical Research · 被引 11)
• A robust platform streamlining aromatic noncanonical amino acid biosynthesis and genetic code expansion in Escherichia coli (2025 · Nature Communications · 被引 9)