Shan Chen

机构：Sun Yat-sen University, China Executive Leadership Academy Pudong, Science for Life Laboratory, Karolinska Institutet, Insilico Biotechnology (Germany) · ORCID：0000-0002-6177-5980

发表论文 36 篇 · 总被引 868 次 · h-index 14

代表论文

• A generative AI-discovered TNIK inhibitor for idiopathic pulmonary fibrosis: a randomized phase 2a trial (2025 · Nature Medicine · 被引 121)
• Effect of Intensive Periodontal Therapy on Blood Pressure and Endothelial Microparticles in Patients With Prehypertension and Periodontitis: A Randomized Controlled Trial (2017 · Journal of Periodontology · 被引 88)
• Increased risks of dental caries and periodontal disease in Chinese patients with inflammatory bowel disease (2020 · International Dental Journal · 被引 65)
• Intestinal mucosal barrier repair and immune regulation with an AI-developed gut-restricted PHD inhibitor (2024 · Nature Biotechnology · 被引 48)
• AEG-1 activates Wnt/PCP signaling to promote metastasis in tongue squamous cell carcinoma (2015 · Oncotarget · 被引 47)
• Association of enhanced circulating trimethylamine N‐oxide with vascular endothelial dysfunction in periodontitis patients (2021 · Journal of Periodontology · 被引 34)