Amit S. Kalgutkar

机构：Pfizer (United States) · ORCID：0000-0001-9701-756X

发表论文 262 篇 · 总被引 15318 次 · h-index 62

代表论文

• A Second-Generation Oral SARS-CoV-2 Main Protease Inhibitor Clinical Candidate for the Treatment of COVID-19 (2024 · Journal of Medicinal Chemistry · 被引 81)
• Discovery of SARS-CoV-2 papain-like protease (PL pro ) inhibitors with efficacy in a murine infection model (2024 · Science Advances · 被引 55)
• Mechanisms of Nitrosamine Mutagenicity and Their Relationship to Rodent Carcinogenic Potency (2024 · Chemical Research in Toxicology · 被引 51)
• Strategies for Assessing Acceptable Intakes for Novel N -Nitrosamines Derived from Active Pharmaceutical Ingredients (2022 · Journal of Medicinal Chemistry · 被引 39)
• Small molecule branched-chain ketoacid dehydrogenase kinase (BDK) inhibitors with opposing effects on BDK protein levels (2023 · Nature Communications · 被引 34)
• Discovery of Ervogastat (PF-06865571): A Potent and Selective Inhibitor of Diacylglycerol Acyltransferase 2 for the Treatment of Non-alcoholic Steatohepatitis (2022 · Journal of Medicinal Chemistry · 被引 29)