Jared Pitts

机构：Gilead Sciences (United States) · ORCID：0000-0003-4080-4321

发表论文 27 篇 · 总被引 1212 次 · h-index 14

代表论文

• Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chimeric SARS-CoV Expressing the SARS-CoV-2 RNA Polymerase in Mice (2020 · Cell Reports · 被引 541)
• Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C -Nucleoside Leading to the Discovery of Remdesivir (GS-5734) as a Potent Inhibitor of Respiratory Syncytial Virus with Efficacy in the African Green Monkey Model of RSV (2021 · Journal of Medicinal Chemistry · 被引 90)
• Remdesivir and GS-441524 Retain Antiviral Activity against Delta, Omicron, and Other Emergent SARS-CoV-2 Variants (2022 · Antimicrobial Agents and Chemotherapy · 被引 77)
• Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucleoside GS-441524 That Exhibits Antiviral Efficacy in SARS-CoV-2-Infected African Green Monkeys (2023 · Journal of Medicinal Chemistry · 被引 63)
• Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells (2021 · Antimicrobial Agents and Chemotherapy · 被引 63)
• Small Molecules Targeting the Flavivirus E Protein with Broad-Spectrum Activity and Antiviral Efficacy in Vivo (2019 · ACS Infectious Diseases · 被引 43)