Aneel K. Aggarwal

机构：Icahn School of Medicine at Mount Sinai · ORCID：0000-0003-4389-0173

发表论文 198 篇 · 总被引 18107 次 · h-index 66

代表论文

• A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models (2021 · Science Translational Medicine · 被引 158)
• H19 influenza A virus exhibits species-specific MHC class II receptor usage (2024 · Cell Host & Microbe · 被引 97)
• Discovery of a dual WDR5 and Ikaros PROTAC degrader as an anti-cancer therapeutic (2022 · Oncogene · 被引 58)
• Discovery of Potent and Selective WDR5 Proteolysis Targeting Chimeras as Potential Therapeutics for Pancreatic Cancer (2023 · Journal of Medicinal Chemistry · 被引 51)
• High-resolution structures of the SARS-CoV-2 N7-methyltransferase inform therapeutic development (2022 · Nature Structural & Molecular Biology · 被引 37)
• Activation of CBASS Cap5 endonuclease immune effector by cyclic nucleotides (2024 · Nature Structural & Molecular Biology · 被引 20)