John M. Wrangle

机构：Memorial Sloan Kettering Cancer Center, Medical University of South Carolina, Cornell University, MUSC Hollings Cancer Center · ORCID：0000-0001-8998-4509

发表论文 116 篇 · 总被引 6237 次 · h-index 25

代表论文

• Safety, Tolerability, and Antitumor Activity of Zipalertinib Among Patients With Non–Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertions (2023 · Journal of Clinical Oncology · 被引 60)
• Phase (Ph) 1/2a study of CLN-081 in patients (pts) with NSCLC with EGFR exon 20 insertion mutations (Ins20). (2022 · Journal of Clinical Oncology · 被引 32)
• IL-15: from discovery to FDA approval (2025 · Journal of Hematology & Oncology · 被引 26)
• Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers (2022 · The Journal of Immunology · 被引 25)
• Zipalertinib in Patients With Epidermal Growth Factor Receptor Exon 20 Insertion-Positive Non–Small Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy With or Without Amivantamab (2025 · Journal of Clinical Oncology · 被引 17)
• Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway (2025 · Nature Communications · 被引 11)