Jennifer Sebalusky

机构：Biogen (United States) · ORCID：0000-0002-9657-875X

发表论文 7 篇 · 总被引 150 次 · h-index 4

代表论文

• Alzheimer disease neuropathology in a patient previously treated with aducanumab (2022 · Acta Neuropathologica · 被引 55)
• Transferrin receptor–targeted anti-amyloid antibody enhances brain delivery and mitigates ARIA (2025 · Science · 被引 53)
• In vivo genome editing using novel AAV-PHP variants rescues motor function deficits and extends survival in a SOD1-ALS mouse model (2022 · Gene Therapy · 被引 28)
• Engineering anti-amyloid antibodies with transferrin receptor targeting improves brain biodistribution and mitigates ARIA (2024 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 13)
• An in vivo model of Amyloid-Related Imaging Abnormalities (ARIA) predicts ARIA incidence of anti-Aβ antibodies seen in clinical trials (2026 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 1)
• Antisense oligonucleotide treatment following viral delivery of artificial SOD1-targeting miRNA shows improved efficacy in SOD1-G93A mice (2026 · Molecular Therapy Advances)