Frank P. McCormick

机构：Leidos (United States), University of California, San Francisco, Frederick National Laboratory for Cancer Research, UCSF Helen Diller Family Comprehensive Cancer Center, U-M Rogel Cancer Center, Leidos Biomedical Research Inc. (United States), University of San Francisco · ORCID：0000-0002-6619-7120

发表论文 826 篇 · 总被引 81866 次 · h-index 130

代表论文

• Discovery of BBO-11818, a Potent and Selective Noncovalent Inhibitor of (ON) and (OFF) KRAS with Activity against Multiple Oncogenic Mutants (2026 · Cancer Discovery · 被引 6)
• Revisiting RAS family GTPase signaling: effector selectivity and oncogenic bypass (2026 · Biochemical Journal · 被引 3)
• The heart of the matter: a personal view of Fred Wittinghofer’s contributions to RAS biology and drug design (2026 · Biological Chemistry · 被引 2)
• Dual inhibition of GTP-bound (ON) and GDP-bound (OFF) KRAS G12C suppresses PI3Kα and leads to potent tumor inhibition (2026 · bioRxiv (Cold Spring Harbor Laboratory) · 被引 1)
• KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamics (2026 · Journal of Biological Chemistry · 被引 1)
• Oncogenic KRAS Rewires mRNA Stability and Translation through AGO2-Mediated Disruption of the miRNA pathway (2026 · Cancer Research)