Zdeněk Hostomský

机构：Pfizer (United States)

发表论文 86 篇 · 总被引 5853 次 · h-index 33

代表论文

• The Crystal Structure of Hepatitis C Virus NS3 Proteinase Reveals a Trypsin-like Fold and a Structural Zinc Binding Site (1996 · Cell · 被引 509)
• Base Excision Repair Is Impaired in Mammalian Cells Lacking Poly(ADP-ribose) Polymerase-1 (2000 · Biochemistry · 被引 504)
• Anticancer Chemosensitization and Radiosensitization by the Novel Poly(ADP-ribose) Polymerase-1 Inhibitor AG14361 (2004 · JNCI Journal of the National Cancer Institute · 被引 489)
• Preclinical selection of a novel poly(ADP-ribose) polymerase inhibitor for clinical trial (2007 · Molecular Cancer Therapeutics · 被引 306)
• Resistance-Modifying Agents. 9. Synthesis and Biological Properties of Benzimidazole Inhibitors of the DNA Repair Enzyme Poly(ADP-ribose) Polymerase (2000 · Journal of Medicinal Chemistry · 被引 289)
• Development of a Functional Assay for Homologous Recombination Status in Primary Cultures of Epithelial Ovarian Tumor and Correlation with Sensitivity to Poly(ADP-Ribose) Polymerase Inhibitors (2010 · Clinical Cancer Research · 被引 270)