John W. R. Schwabe

机构：University of Leicester, Institute of Molecular and Cell Biology, Institute for Structural Research, Institute of Structural and Molecular Biology · ORCID：0000-0003-2865-4383

发表论文 195 篇 · 总被引 16042 次 · h-index 64

代表论文

• Optimization of Class I Histone Deacetylase PROTACs Reveals that HDAC1/2 Degradation is Critical to Induce Apoptosis and Cell Arrest in Cancer Cells (2022 · Journal of Medicinal Chemistry · 被引 80)
• Histone H2B Deacylation Selectivity: Exploring Chromatin’s Dark Matter with an Engineered Sortase (2022 · Journal of the American Chemical Society · 被引 69)
• Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate (2021 · Nature Communications · 被引 68)
• In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding (2022 · PLoS Pathogens · 被引 60)
• Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake (2023 · Science · 被引 59)
• The topology of chromatin-binding domains in the NuRD deacetylase complex (2020 · Nucleic Acids Research · 被引 52)