Wei‐Shuo Fang

机构：Chinese Academy of Medical Sciences & Peking Union Medical College · ORCID：0000-0002-0972-0640

发表论文 110 篇 · 总被引 1804 次 · h-index 26

代表论文

• Structural insight into the stabilization of microtubules by taxanes (2023 · eLife · 被引 70)
• Taxanes convert regions of perturbed microtubule growth into rescue sites (2019 · Nature Materials · 被引 65)
• A Series of Enthalpically Optimized Docetaxel Analogues Exhibiting Enhanced Antitumor Activity and Water Solubility (2018 · Journal of Natural Products · 被引 44)
• Synthesis and biological evaluations of chalcones, flavones and chromenes as farnesoid x receptor (FXR) antagonists (2017 · European Journal of Medicinal Chemistry · 被引 20)
• Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions (2017 · European Journal of Medicinal Chemistry · 被引 14)
• Discovery of a series of selective and cell permeable beta-secretase (BACE1) inhibitors by fragment linking with the assistance of STD-NMR (2019 · Bioorganic Chemistry · 被引 11)