Ryan P. Bingham

机构：Age UK · ORCID：0000-0001-7990-224X

发表论文 34 篇 · 总被引 1525 次 · h-index 14

代表论文

• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation (2015 · Nature Chemical Biology · 被引 772)
• Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition (2019 · Proceedings of the National Academy of Sciences · 被引 173)
• Discovery, SAR, and X-ray Binding Mode Study of BCATm Inhibitors from a Novel DNA-Encoded Library (2015 · ACS Medicinal Chemistry Letters · 被引 82)
• Discovery and Optimization of Potent, Selective, and in Vivo Efficacious 2-Aryl Benzimidazole BCATm Inhibitors (2016 · ACS Medicinal Chemistry Letters · 被引 44)
• The Discovery of in Vivo Active Mitochondrial Branched-Chain Aminotransferase (BCATm) Inhibitors by Hybridizing Fragment and HTS Hits (2015 · Journal of Medicinal Chemistry · 被引 43)
• Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short- and Long-Distance Conformational Changes (2019 · Journal of Medicinal Chemistry · 被引 38)