Joann Strnad

发表论文 36 篇 · 总被引 2341 次 · h-index 18

代表论文

BMS-345541 Is a Highly Selective Inhibitor of IκB Kinase That Binds at an Allosteric Site of the Enzyme and Blocks NF-κB-dependent Transcription in Mice (2003 · Journal of Biological Chemistry · 被引 550)
Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165 (2019 · Journal of Medicinal Chemistry · 被引 381)
Autoimmune pathways in mice and humans are blocked by pharmacological stabilization of the TYK2 pseudokinase domain (2019 · Science Translational Medicine · 被引 292)
A Novel Peptidylarginine Deiminase 4 (PAD4) Inhibitor BMS-P5 Blocks Formation of Neutrophil Extracellular Traps and Delays Progression of Multiple Myeloma (2020 · Molecular Cancer Therapeutics · 被引 148)
Identification of N-Methyl Nicotinamide and N-Methyl Pyridazine-3-Carboxamide Pseudokinase Domain Ligands as Highly Selective Allosteric Inhibitors of Tyrosine Kinase 2 (TYK2) (2019 · Journal of Medicinal Chemistry · 被引 95)
Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Binds to Tyk2 JH2 (2020 · Journal of Medicinal Chemistry · 被引 88)