Mark S. Albom

发表论文 52 篇 · 总被引 1455 次 · h-index 22

代表论文

Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK) (2016 · Journal of Medicinal Chemistry · 被引 91)
CEP-28122, a Highly Potent and Selective Orally Active Inhibitor of Anaplastic Lymphoma Kinase with Antitumor Activity in Experimental Models of Human Cancers (2011 · Molecular Cancer Therapeutics · 被引 73)
A Selective, Orally Bioavailable 1,2,4-Triazolo[1,5- a ]pyridine-Based Inhibitor of Janus Kinase 2 for Use in Anticancer Therapy: Discovery of CEP-33779 (2012 · Journal of Medicinal Chemistry · 被引 63)
Synthesis and Biological Profile of the pan-Vascular Endothelial Growth Factor Receptor/Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor-Like Homology Domains 2 (VEGF-R/TIE-2) Inhibitor 11-(2-Methylpropyl)-12,13-dihydro-2-methyl-8-(pyrimidin-2-ylamino)-4 H -indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one (CEP-11981): A Novel Oncology Therapeutic Agent (2011 · Journal of Medicinal Chemistry · 被引 42)
Discovery of an Orally Efficacious Inhibitor of Anaplastic Lymphoma Kinase (2012 · Journal of Medicinal Chemistry · 被引 40)
Design, Synthesis, and Anaplastic Lymphoma Kinase (ALK) Inhibitory Activity for a Novel Series of 2,4,8,22-Tetraazatetracyclo[14.3.1.1 3,7 .1 9,13 ]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaene Macrocycles (2011 · Journal of Medicinal Chemistry · 被引 40)