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Andrew A. Mortlock

机构:Astellas Pharma (United Kingdom) · ORCID:0009-0001-3858-5804

发表论文 77 篇 · 总被引 2929 次 · h-index 23

代表论文

  • Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores (2003 · The Journal of Cell Biology · 被引 1205)
  • AZD1152, a Selective Inhibitor of Aurora B Kinase, Inhibits Human Tumor Xenograft Growth by Inducing Apoptosis (2007 · Clinical Cancer Research · 被引 361)
  • Discovery, Synthesis, and in Vivo Activity of a New Class of Pyrazoloquinazolines as Selective Inhibitors of Aurora B Kinase (2007 · Journal of Medicinal Chemistry · 被引 275)
  • SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors (2005 · Bioorganic & Medicinal Chemistry Letters · 被引 127)
  • Discovery of Novel and Potent Thiazoloquinazolines as Selective Aurora A and B Kinase Inhibitors (2006 · Journal of Medicinal Chemistry · 被引 92)
  • Progress in the Development of Selective Inhibitors of Aurora Kinases (2005 · Current Topics in Medicinal Chemistry · 被引 75)