Mark Eric Kohler

机构：Children's Hospital Colorado, Center for Cancer and Blood Disorders, University of Colorado Anschutz, University of Colorado Denver · ORCID：0000-0002-1181-0418

发表论文 73 篇 · 总被引 2879 次 · h-index 16

代表论文

• CD33 CAR T-Cells (CD33CART) for Children and Young Adults with Relapsed/Refractory AML: Dose-Escalation Results from a Phase I/II Multicenter Trial (2023 · Blood · 被引 67)
• Potent preclinical activity of FLT3-directed chimeric antigen receptor T-cell immunotherapy against FLT3- mutant acute myeloid leukemia and KMT2A-rearranged acute lymphoblastic leukemia (2022 · Haematologica · 被引 54)
• Digital polymerase chain reaction strategies for accurate and precise detection of vector copy number in chimeric antigen receptor T-cell products (2022 · Cytotherapy · 被引 23)
• Restoration of LAT activity improves CAR T cell sensitivity and persistence in response to antigen-low acute lymphoblastic leukemia (2025 · Cancer Cell · 被引 20)
• Antigen experience history directs distinct functional states of CD8+ CAR T cells during the antileukemia response (2025 · Nature Immunology · 被引 19)
• Deleting the mitochondrial respiration negative regulator MCJ enhances the efficacy of CD8+ T cell adoptive therapies in pre-clinical studies (2024 · Nature Communications · 被引 18)