Kirsten M. Knecht

机构：Yale University · ORCID：0000-0001-5892-3770

发表论文 29 篇 · 总被引 474 次 · h-index 11

代表论文

• SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways (2018 · Proceedings of the National Academy of Sciences · 被引 122)
• Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML (2019 · Nature Communications · 被引 85)
• The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1 (2018 · Proceedings of the National Academy of Sciences · 被引 63)
• A bacterial riboswitch class for the thiamin precursor HMP-PP employs a terminator-embedded aptamer (2019 · eLife · 被引 38)
• SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4 + T Cells (2018 · Journal of Virology · 被引 34)
• The SAM domain of mouse SAMHD1 is critical for its activation and regulation (2018 · Nature Communications · 被引 23)