Jillian E. Spangler

机构：Pfizer (United States), Université Bourgogne Franche-Comté

发表论文 64 篇 · 总被引 3356 次 · h-index 17

代表论文

• Hindered dialkyl ether synthesis with electrogenerated carbocations (2019 · Nature · 被引 399)
• Strain-Release Heteroatom Functionalization: Development, Scope, and Stereospecificity (2017 · Journal of the American Chemical Society · 被引 355)
• Optimization of Orally Bioavailable Enhancer of Zeste Homolog 2 (EZH2) Inhibitors Using Ligand and Property-Based Design Strategies: Identification of Development Candidate ( R )-5,8-Dichloro-7-(methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-3,4-dihydroisoquinolin-1(2 H )-one (PF-06821497) (2017 · Journal of Medicinal Chemistry · 被引 129)
• 1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long–sought-after mimetics for ortho / meta -substituted arenes (2021 · Proceedings of the National Academy of Sciences · 被引 123)
• 1,2-Difunctionalized Bicyclo[1.1.1]pentanes: Long Sought After Bioisosteres for ortho/meta-Substituted Arenes (2020 · ChemRxiv · 被引 6)
• Hindered Dialkyl Ether Synthesis via Electrogenerated Carbocations (2019 · ChemRxiv · 被引 5)