Jos H. Beijnen
ORCID：0000-0003-0118-561X
发表论文 1772 篇 · 总被引 76929 次 · h-index 129
代表论文
- Intestinal human carboxylesterase 2 (CES2) expression rescues drug metabolism and most metabolic syndrome phenotypes in global Ces2 cluster knockout mice (2024 · Acta Pharmacologica Sinica · 被引 14)
- Dose-individualisation of fluoropyrimidines based on pre-treatment serum uracil levels: the Alpe2U study (2025 · European Journal of Cancer · 被引 13)
- A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAF V600 -Mutated Melanoma (2024 · Clinical Cancer Research · 被引 13)
- Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune‐related adverse events of immune checkpoint inhibitors (2024 · Cancer Medicine · 被引 12)
- ATP-binding cassette transporter inhibitor potency and substrate drug affinity are critical determinants of successful drug delivery enhancement to the brain (2024 · Fluids and Barriers of the CNS · 被引 9)
- ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure (2024 · Biomedicine & Pharmacotherapy · 被引 8)