John Sembrat

机构：University of Pittsburgh, Pulmonary and Allergy Associates · ORCID：0000-0003-4108-803X

发表论文 233 篇 · 总被引 5539 次 · h-index 35

代表论文

• Inhibition of epithelial cell YAP-TEAD/LOX signaling attenuates pulmonary fibrosis in preclinical models (2025 · Nature Communications · 被引 24)
• A deep generative model for deciphering cellular dynamics and in silico drug discovery in complex diseases (2025 · Nature Biomedical Engineering · 被引 21)
• Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation (2026 · Nature Communications · 被引 12)
• Endothelial ADAR1 Deficit Induces the NOCT-IRF7 Axis in Pulmonary Hypertension (2025 · Circulation Research · 被引 7)
• Targeting cannabinoid receptor 1 for antagonism in pro-fibrotic alveolar macrophages mitigates pulmonary fibrosis (2025 · JCI Insight · 被引 5)
• VX-445 (elexacaftor) inhibits chloride secretion across human bronchial epithelial cells by directly blocking KCa3.1 channels (2025 · PNAS Nexus · 被引 5)