Linda Bao

发表论文 10 篇 · 总被引 356 次 · h-index 6

代表论文

• Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer (2011 · Journal of Medicinal Chemistry · 被引 218)
• Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349 (2012 · ACS Medicinal Chemistry Letters · 被引 46)
• In Vitro and In Vivo Evaluation of Amorphous Solid Dispersions Generated by Different Bench-Scale Processes, Using Griseofulvin as a Model Compound (2013 · The AAPS Journal · 被引 33)
• Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease (2024 · Journal of Medicinal Chemistry · 被引 23)
• On Demand Bioorthogonal Switching of an Antibody-Conjugated SPECT Probe to a Cytotoxic Payload: from Imaging to Therapy (2024 · Journal of the American Chemical Society · 被引 19)
• Optimization of a Novel DEL Hit That Binds in the Cbl-b SH2 Domain and Blocks Substrate Binding (2024 · ACS Medicinal Chemistry Letters · 被引 14)