Xiaoke Guo

机构：China Pharmaceutical University, State Key Laboratory of Natural Medicine · ORCID：0000-0002-7558-5504

发表论文 93 篇 · 总被引 1532 次 · h-index 22

代表论文

• Multi-Water Bridges Enable Design of BET BD1-Selective Inhibitors for Pancreatic Cancer Therapy (2025 · Journal of Medicinal Chemistry · 被引 11)
• Discovery of WDR5–MLL1 and HDAC Dual-Target Inhibitors for the Treatment of Acute Myeloid Leukemia (2025 · Journal of Medicinal Chemistry · 被引 10)
• Discovery of the salicylaldehyde-based compound DDO-02267 as a lysine-targeting covalent inhibitor of ALKBH5 (2024 · European Journal of Medicinal Chemistry · 被引 10)
• Discovery of Selenium-Containing Derivatives as Potent and Orally Bioavailable GLP-1R Agonists (2025 · Journal of Medicinal Chemistry · 被引 9)
• Supramolecular Host–Guest Assemblies for Tunable and Modular Lysosome‐Targeting Protein Degradation (2025 · Angewandte Chemie International Edition · 被引 8)
• Rational Design of Novel Quinazolinone–Pyrrolodihydropyrrolone Analogs as PIM/HDAC Dual-Target Inhibitors for the Treatment of Acute Myelocytic Leukemia (2025 · Journal of Medicinal Chemistry · 被引 8)